Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 20 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-alpha Tocopheryl Acetate)
268 mg
1787%
Top Medical Research Studies
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More
Most Useful Reviews
9
Cramps disappeared
30 people found this helpful
I have suffered from severe leg cramps, and after being advised to take this supplement for about 3 months, I noticed a reduction in pain. By the second month, the pain had entirely vanished! Previously, it was so intense that I struggled to walk, but now I can manage comfortably without issues. I will continue to take it.
Read More
9
No painkillers needed
8 people found this helpful
Practising the Fujikawa method, I felt relief from leg cramps with one tablet daily, but when I upped it to two, the cramps vanished completely. I no longer need painkillers. I’ve shared it with family and friends, and they had similar experiences. The soft capsules are easy to swallow, so I highly recommend it!
Read More
9
Reduced blood clots
4 people found this helpful
While it's often hard to notice effects from supplements, I was amazed at how much my leg cramps lessened after taking one tablet in the morning and evening. The clotting during my period has virtually disappeared. This product genuinely feels like it purifies the blood, and I take it regularly now.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Read More
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
Read More
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Cramps disappeared
30 people found this helpful
I have suffered from severe leg cramps, and after being advised to take this supplement for about 3 months, I noticed a reduction in pain. By the second month, the pain had entirely vanished! Previously, it was so intense that I struggled to walk, but now I can manage comfortably without issues. I will continue to take it.
Read More
9
No painkillers needed
8 people found this helpful
Practising the Fujikawa method, I felt relief from leg cramps with one tablet daily, but when I upped it to two, the cramps vanished completely. I no longer need painkillers. I’ve shared it with family and friends, and they had similar experiences. The soft capsules are easy to swallow, so I highly recommend it!
Read More
9
Reduced blood clots
4 people found this helpful
While it's often hard to notice effects from supplements, I was amazed at how much my leg cramps lessened after taking one tablet in the morning and evening. The clotting during my period has virtually disappeared. This product genuinely feels like it purifies the blood, and I take it regularly now.
Read More
10
No more cramps
I take one pill daily, and since incorporating it into my routine, I no longer suffer from menstrual cramps.
Read More
10
Easier to swallow
This vitamin E is small and easy to swallow. It has relieved my menstrual cramps, unlike larger pills from other brands.
Read More
Frequently Asked Questions
9
Quick relief
For leg cramps, I take E-vitamin 400IU, and within a minute, the cramps disappear without pain. This method has worked for years.
9
Cramps disappeared
30 people found this helpful
I have suffered from severe leg cramps, and after being advised to take this supplement for about 3 months, I noticed a reduction in pain. By the second month, the pain had entirely vanished! Previously, it was so intense that I struggled to walk, but now I can manage comfortably without issues. I will continue to take it.
9
No painkillers needed
8 people found this helpful
Practising the Fujikawa method, I felt relief from leg cramps with one tablet daily, but when I upped it to two, the cramps vanished completely. I no longer need painkillers. I’ve shared it with family and friends, and they had similar experiences. The soft capsules are easy to swallow, so I highly recommend it!
7.5
Pain alleviated
3 people found this helpful
After many years of leg cramps and recurring uterine fibroids, my painful symptoms have eased significantly a month after starting this supplement. I intend to keep taking it daily from now on.
10
No more cramps
I take one pill daily, and since incorporating it into my routine, I no longer suffer from menstrual cramps.
9
Bleeding reduction
I've taken vitamin E every morning for over six months. It has significantly reduced my menstrual cramps and bleeding. I plan to continue my intake.
7.5
Overall health boost
2 people found this helpful
I alternate between this and another supplement, and my overall health, skin, and motivation have improved. Although I'm also taking various other vitamins, this product effectively alleviates leg cramps too. It's highly recommended.
9
Pain relief
3 people found this helpful
I've used this natural vitamin E for three years. When I have menstrual cramps, taking more helps relieve the pain, although it has a slight smell.
7
Vitamin E effective for leg cramps
We explored the effects of vitamin E on leg cramps through a controlled double-blind study involving 40 dialysis patients.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
After a two-month placebo washout, participants were split into two groups receiving either quinine or vitamin E.
Both treatments significantly reduced the number of leg cramps. With average monthly cramps dropping to around 3.3 for vitamin E and 3.6 for quinine, the findings indicate both options were effective.
However, since quinine has potential side effects, vitamin E is recommended as the first-line treatment for leg cramps in this population.
9
We investigated the impact of vitamin E on treating frequent and severe nocturnal leg cramps. Patients received 100 I.U. of d, alpha-tocopheryl acetate three times daily before meals.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
Remarkably, nearly all participants reported prompt relief from their symptoms. This group included 24 patients with leg cramps and a couple with "restless legs" syndrome.
Given that nocturnal leg cramps can be distressing and treatments are often unsatisfactory, these findings are particularly noteworthy.
7
Vitamin E shows limited effectiveness
We examined the effectiveness of various treatments for leg cramps, focusing particularly on vitamin E. While quinine has long been a go-to option, its use has significantly decreased due to safety concerns and mixed results in studies. Our review highlighted that although vitamin E might show potential benefits for leg cramps in patients on dialysis, the evidence is not robust across all populations. Therefore, we should consider other medications, like verapamil or gabapentin, before reverting to quinine.
References
- Guay DR. Are there alternatives to the use of quinine to treat nocturnal leg cramps?. Consult Pharm. 2008;23:141.
- Roca AO, Jarjoura D, Blend D, Cugino A, Rutecki GW, et al. Dialysis leg cramps. Efficacy of quinine versus vitamin E. ASAIO J. 1992;38:M481.
- Ayres S, Mihan R. Leg cramps (systremma0 and "restless legs" syndrome. Response to vitamin E (tocopherol). Calif Med. 1969;111:87.
